Group Archives: Prescribing

Are NICE not being nice to GPs about antibiotics?

The new Antimicrobial Stewardship guidance was published this month by NICE, looking at organisational and system-wide approaches to optimising antimicrobial use. And the main message coming out of various news agencies today is that GPs will be “struck off” for not prescribing antibiotics appropriately. There is, of course, huge concern around the rising amount of …read more

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Drug safety in a world of multimorbidity and polypharmacy

New research describes an association between use of two commonly used medications and brain haemorrhage. CCHSR’s Rupert Payne doesn’t necessarily think it’s that straightforward.

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So will pharmacists save the NHS?

Well maybe, but we shouldn’t get too carried away. The RCGP and RPS have produced a joint statement of how pharmacists and GPs could work better together and the news media today are talking about an ‘army’ of pharmacists coming to the rescue of general practice. Should we be greeting the cavalry with open arms? …read more

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Don’t incentivise withholding of antibiotics!

Don’t prescribe too many antibiotics. And just to make sure you behave, we’ll pay you not to. That’s the latest message GPs are being given by the government. I personally find this very irritating. GPs are well aware of the public health implications of prescribing too many antibiotics, and the consequent risks of antibiotic resistance. …read more

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Medication errors in primary care in the developing world

Global spending on pharmaceuticals is roughly a $1 trillion, dominated by the US, Japan and major EU economies. Yet emerging markets and the developing world still account for around a third of expenditure. That’s a lot of medicines and it’s growing. With this substantial use of medications comes a significant risk of harm, compounded by …read more

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Medicalising life

Medicines have been getting into the mainstream news quite a lot in recent times. A couple of days ago saw the publication in Annals of Oncology of a review of the evidence for a protective effect of aspirin in reducing cancer in the general population. The role of aspirin in cardiovascular disease prevention is well …read more

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The King’s Fund: Polypharmacy and Medicines Optimisation

Policy, medical training and clinical practice have failed to adapt to a significant increase in the number of patients taking multiple prescription drugs, according to a new report published by The King’s Fund. CCHSR’s Rupert Payne co-authored the report, and discusses its implications.

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Are ACE inhibitors not as ace as we thought?

ACE inhibitors and “sartans” are the NHS’s second most commonly prescribed drugs, used to treat a range of cardiovascular problems. Work by members of CCHSR published in the journal PLOS One shows that their increasing use appears to be strongly associated with acute kidney injury.

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Medication safety and the real world of general practice

Clinical trials are carefully designed to establish the efficacy and safety of new drugs. But how relevant are they to the real-world setting of general practice? And what can general practice do to try and help research into drug safety?

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Inappropriate medicines and prescribing – why it matters

Over the last year, the English NHS spent £10 billion on prescribing around a billion items in primary care. Yet a substantial amount of medication use may be potentially inappropriate. How can we as researchers potentially address this problem?

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